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Namu Myoho Renge Kyo,
Ryuei
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The text commentaries, while useful and appropriate, are limited to the original applications of the herbal formulas described in the Shang Han Lun. It is disappointing that the authors chose not to cover later applications of these formulas, as the inclusion of such material would have made the text authoritative. However, what the work lacks in breadth, it makes up for in depth by being the most comprehensive and unadulterated look at the original Shang Han Lun system of herbal medicine available in English.
Unfortunate is the adoption of coauthor Nigel Wiseman's exotic English terms for traditional Chinese medical phrases, which are uniformly neologisms or new, awkward usage of existing and often unrelated English words. This choice makes for difficult reading, but Mr Wiseman's terms are explained in detail both in situ and in the excellent glossary section of this book. Liberal use of the glossary will make clear to the reader words and turns of phrase which otherwise seem designed to obfuscate.
Despite a few faults, this book is a landmark translation for the English-speaking practitioner of Chinese medicine wishing to study the theory and practice of the Shang Han Lun, or to begin learning ancient medical Chinese. What it may lack in the details of execution, it more than makes up for with an overall solid translation, including the original Chinese text, and a useful glossary. The coauthors manage to convey a clear sense of this way of looking at infectious diseases and epidemiology, a way very different from the modern Western view, but also eerily similar on closer examination. This book will be welcomed, both by the clinician and the advanced student.
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The book is good for biostatisticians and regulatory affairs specialists as a reference source. All the key statistical issues are addressed and the reader is given the perspective of the ICH and FDA guidance documents. The underlying statistical methodology that justifies the recommendations in the guidances is presented. This is a state-of-the-art book. Shao and Pigeot produced some of the recent research in individual bioequivalence that established a bootstrap procedure as an appropriate way to construct confidence intervals for the problem. Their method is recommended in an FDA guidance document.
But more than just this one example, all the key issues that have been the subject of FDA workshops over the past several years are addressed in this book. These topics include calibration, assay and assay validation, dissolution testing, stability analysis, shelf life estimation, bioequivalence, randomization and blinding, what constitutes substantive evidence in clinical development, therapeutic equivalence and noninferiority, Bayesian approaches in clinical trials, problems involving missing and incomplete data, longitudinal methods, meta-analysis, quality of life studies and instrument validation, and medical imaging.
Other prevalent issues in clinical trials include group sequential methods, hierarchical Bayesian models and multiple testing. These issues are not covered as much in this text as the others we have mentioned. But there is some discussion of multiplicity in the context of quality of life studies. An example of sequential testing is used to illustrate model selection in Chapter 2. The important issues of design and sample size requirements are presented throughout the book.
While not all topics are covered in sufficient depth, the book is remarkable in the breadth of material covered in just 350 pages of text. The authors also provide a very authoritative list of references and regulatory guidances and other documents.
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It is difficult to put into words the boundless joy that accompanies the reading of these letters. Here is Lowry at his most winkingly self-deprecatory, literarily allusive and, above all, charming and downright funny. For anyone who values the English Language and English literature highly; as, in fact, necessary to life, as Lowry did, these letters will hold you spellbound. Here is indeed the record of a man who, quite literally, lived and died for language and literature. As his most famous letter here, the one to his publisher which ultimately led to the publication of Under The Volcano, has it, "...but just the same in our Elizbethan days we used to have at least passionate poetic writing about things that will always mean something and not just silly ... style and semicolon technique: and in this sense I am trying to remedy a deficiency, to strike a blow, to fire a shot for you as it were, roughly in the direction, say, of another Renaissance: it will probably go straight through my brain but that is another matter."
It is clear from almost every letter here, that Lowry was trying his damnedest,in all his writings, to live up to this manifesto; that, despite the continual tragedies of his life, he was always picking himself up and wringing from his life "passionate poetic writing", which, it is clear from these letters, was, to a great extent, lived as a literary endeavour.
That the shot did eventually go through his brain, so to speak, was not entirely unexpected by Lowry or anyone who knew him. - But neither was Sir Walter Ralegh's unjust execution. - Ultimately then, these collected letters live up to the title: Sursum Corda!-Lift up your hearts!-Here is page upon page of writing about things that will always mean something: Love of life, literature, words and a delight in language in and of itself.-
Unrealistic though my expectaation of their reading of these two massive tomes may be, I would recommend them to anyone who suffers from the peculiar fate of being human.
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But the author Luo Kwang Chung wasn't being fair to every character. ChaoChau was written as an evil conspirator and LiuBei was potraited to be a great hero. But was it really that way? In real history, the time of the Three kingdoms didn't had a clear distinct between evil and good, but the author wrote it in this way as in his own sympathy to Liubei, which in ancient China was more popular for his loyal to the Han dynasty and sympathy to the peasants.
Nevertheless, that's why this is called a historic novel and not 'facts'. So any people reading this book: Read it as a novel and not a history textbook.
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This book has its sad moments particularly when someone important or someone who contributed a lot to his lord dies. You'll feel sympathetic towards those who fought hard as well as the ones who died. When the book starts, it's during the impending collapse of the Han then around 220 is when the real three kingdoms come into play: Shu, Wu, and Wei. It's sort of like a battle to the death of who would emerge victorious and indeed there was. Military tactics are exploited on each side and betrayal is widespread. In the end, it would be Sima Yi's family who would unite China under one rule, the Jin Dyansty.