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The book is divided into formal parts, beginning with Part I: Chemistry, and progressing through biochemistry and clinical applications; ending with Part IV: New Platinum Drugs for the Future. Each of the three or four sub-sections in each Part is written by leaders in those areas. Moreover, the book is very evenly balanced between basic science and clinical research. The plethora of literature references in each sub-section is current, and the figures and tables are all very well done.
Of course, cancer research changes very quickly. However, even after the book by Kelland and Farrell is out of date it can still serve as an excellent primer for graduate and medical students wishing to learn the ins and outs of platinum medical science. This book will certainly serve as a superb model for similar monographs of the future.
For those who do have a tertiary background in science, particularly in chemistry, they will find that this book one of the best publications ever. Written by two experts in the field Professor Nicholas Farrell (Virginia Commonwaelth University) and Professor Lloyd Kelland (Institute of Cancer Reserach England), the book covers all areas of platinum chemistry from synthesis and DNA binding to cytotoxicity and cellular uptake.
As a single publication this book is an excellent review of all major work that has occurred since the discovery of cisplatin in the late 1960's.
This book is a definite must for scientists entering, or already conducting research into platinum chemotherapy.
In my theological education, many of my professors are heavily or primarily influenced by and adherents of process theology. It makes sense that I too would have a keen interest in this topic. Having more than a passing interest, I opted to study further under the rubrics of a guided research the underlying philosophy of this theology.
Nicholas Rescher is a professor of philosophy at the University of Pittsburg. This particular volume is part of the SUNY Series in Philosophy. There are in fact several introductions and explanations of process philosophy (several more of which I shall likely write upon here). In the introduction, Rescher explains the importance and some of the success of process philosophy:
'Process metaphysics as a general line of approach holds that physical existence is at bottom processual; that processes rather than things best represent the phenomena that we encounter in the natural world about us.'
Rescher begins in the first chapter with an historical survey, looking at various points in ancient and more recent philosophical systems that provide seeds for process thought. He states that the true father of process thought is Heraclitus, the philosopher from the 6th century BCE, who wrote of nature as process. Plato, in endorsing Heraclitus, continues some process ideas. Leibniz, Hegel, Pierce, James, Bergson, Dewey, and Sheldon are all held up, together with Whitehead, as key to the development of process thought as it is formulated today.
'No philosophical position as such is defined by its historical exponents; it is at most exemplified by them. And, in fact, the process-oriented approach in metaphysics is historically too pervasive and systematically too significant to be restricted in its bearing to one particular philosopher and his adherents.'
One of the difficulties at pinning down process philosophy, particularly metaphysics, is that it is less of a doctrine and more of a trend, or tendency, or overarching framework.
'It can be developed in very different directions, varying with the question of what sort of process one takes to be paradigmatic or fundamental. If it is a mechanical or physical process, one sort of doctrine results (a materialism of some sort), while if it is mental or psychical, a very different sort of doctrine results (an idealism of some description).'
Rescher takes one through the key concepts and categories -- like all philosophies, it has its own vocabulary. There are different kinds of processes. There are different kinds of relationships of process with particulars, and process with universals. Particulars end up being less static items as being matrices of process, embodiments, as it were. Universals is a tricky problem for metaphysics generally -- in process, universals are generally demoted from the lofty heights a Platonic framework might give them and put into the processes themselves.
Rescher continues from these basic chapters to developing ideas about process and nature, process and persons, process logic and epistemology, and process views of scientific inquiry. However, it is to the final two chapters, Process Theology and Process in Philosophy, that I wish to devote more attention.
In Process Theology, Rescher frankly states the situation that not all process philosophers care about theological ideas. God is seen less as a substance (with all the problems that that view entails) and more of a process. However, God is not part of the physical processes of the world. There is no easy way of visualising God's participation in the world, not being of the world, but there is an interconnectedness, and the issue of how is, according to Rescher, secondary.
'Even apart from process philosophy, various influential theologians have in recent years urged the necessity and desirability of seeing God not through the lens of unchanging stability but with reference to movement, change, development and process.'
God is not a God of mighty acts and deeds in process thinking. God is rather a persuasive force. God does not act directly in the world in a substantive way, but rather in a processual way. God as a personal entity who relates to the world is made much easier to reconcile in a process framework.
'The philosophy of process is also a philosophy in process.'
What is the bottom line with process philosophy? Largely, it is the same as the bottom line with any philosophical system. Can it make sense? Does it explain the details as well as possess a coherence that is rational? How can process philosophy, a philosophy that changes, possess such coherence? Rescher resists the urge to set out a 'decisive, knock-down drag-out argumentation' whose power of persuasion would be 'somewhere between miniscule and nonexistent.' He does, however identify many of the key problems with substance philosophical systems and the smooth and promising fruits of process thinking, not least of which are its compatibility with modern social, scientific, and theological ideas.
This book by Rescher is not for the casual reader. For the advanced undergraduate or graduate student who has at least some background in philosophy, this is a good introduction. Some of the chapters require specialised knowledge -- Rescher's explanation of the difficulties of substantialism in chapter three on particulars employs logic formulae with no explanation; those without training in elementary symbolic logic will likely get lost in this discussion. However, for those who are getting deeper into philosophy or theology, this book will be enlightening and interesting.
Rescher explains also how Whitehead seemed to somewhat cave into the essentialist view by positing 'actual occasions' as basic units of process akin to the atomist view of substance metaphysicians. Rescher tells us that there is no need to posit these basic processual units, but we can go even further than that: empirical evidence would suggest that such units do not exist. With what we know from QM, it appears that the world is held together by processes, illustrated by quantum mechanical wave functions, 'all the way down' with no discernable basic processual unit (and furthermore, might the insertion of something basic, be it a process or a 'thing', contradict the spirit of QM itself?). Rescher thinks that by adopting this view which is more at home with Sheldon (and Teilhard de Chardin) and later process thinkers, process metaphysics rests itself on even more solid foundations.
After reading this book it has become difficult for me to read even Paul Tillich who's otherwise interesting theology is couched in the Platonic language that seems so horribly archaic now. The implication of this would be that Plato and Aristotle (and thus the entire Western tradition) just plain got it wrong about metaphysics and have led us on a wild goose chase to prop up an outlook about the 'first things' that was doomed to fail. It has only been thanks to the cunning insights of Hume and Kant and, even more, the discoveries of science that many philosophers have given up on substance metaphysics and see a process perspective as the only one that could work (if any do). Rescher also speaks very highly of Henri Bergson as prototypical process philosopher which is interesting considering that Teilhard thought so highly of him.
What I respect and admire about his writing is that he brings reality to his characters. The reality he is able to convey is not some stark picture of poverty or prejudice or some equally profound aspect of society, but the frustration a lawyer feels with uncooperative clients, the unfathomability of attitudes and opinions alien to us, and the natural tensions of relationships.
I think we can all agree that Significant Others aren't always soul-mates who complement what is lacking in ourselves. Certainly our children say and do things that are totally incomprehensible to us. Gideon Page, the lawyer protagonist in Grif Stockley's novels, suffers a double slap in the face when his daughter and his girlfriend join a charismatic fundamentalist congregation, exercising religion in a way Gideon seems to feel is the antithesis of free conscious reason and thought. Then, to make matters worse, he is confronted by that same church when the preacher's daughter becomes his client.
Assertive, charismatic, Christian fundamentalism can be bewildering and even offensive to those who view themselves as more "mainstream" or perhaps don't actively practice much religion at all. Confronted with this church and its charismatic preacher, Gideon is repulsed. He is thrust into close contact with not only the preacher and his client, but with the preacher's family and the spooky wife and child of his co-counsel, Chet Bracken.
Despite what some non-lawyers may believe, many, many clients are uncooperative, secretive, and completely untruthful with their attorneys. Lots of times clients have something to hide, or want to accomplish something they know their lawyer wouldn't condone. How many times has every trial lawyer in America said to an uncooperative client, "You MUST tell me everything because unless I know absolutely everything I can't protect you from anything"? Gideon Page has not only an uncooperative client, but an uncooperative co-counsel on this case, though. Not only is the client avoiding him, but Chet Bracken, the lawyer who asked Gideon to help with the case, won't come clean about it. And now Chet is dying and Gideon is going to have to handle the case without knowing anything about it. Frantically investigating every miniscule lead, Gideon's worst fear comes to be that his client might actually be innocent.
When it becomes obvious that Chet Bracken isn't preparing for trial, Gideon attempts to do his best in a virtual vaccuum. Nobody will tell him the truth. Bit by agonizing bit he learns disparate facts that still don't make sense. The investigative trail seems to lead suspiciously to the preacher himself -- is the daughter going to take a fall for Daddy so Daddy won't lose his flock? But wait -- is Daddy going to take a fall for darling daughter? Who really committed the crime? Daughter isn't talking, Daddy talks too much, and co-counsel is cryptic at best.
As trial looms closer Gideon becomes frantic that the legal team has no defense for the accused, and still the accused adamantly refuses even to talk to him! The eleventh hour comes and goes and Gideon finally learns two stupefying facts that change not only his opinion about Chet Bracken, but about Chet's family, the accused, and ... well, I'm not going to give it all away. Read the book! It's worth it!
In fact, it is not a legal thriller at all. The protagonists enter the courtroom only towards the end of the book and then only for a brief period.
It is much more a story about the relationship between father and daughter. Gideon and Sarah go through a very difficult time together when Gideon has to defend a girl who is suspected of killing her husband. Gideon wants to attack in his case the girl's father, a highly respected preacher to whose church Sarah is drawn.
The doubts of Gideon as a father and the complete lack of doubt and the righteousness of Sarah are beautifully drawn. A very satisfactory read.
The pictures and instructions are very user friendly, and easy to follow. And the items that they use are not hard to find. It's not like when you watch a home decorating show and you think," I love how that looks, but where do I find it!? " The book uses things like slate roof tiles and axe handles to create the most appealing things. I mean, when you see how they use and old shutter to make a cd rack you will be amazed!
Salvage Style for Your Home is every frugal home decorator's dream book! It's a book of inspiration and I highly suggest you give it a read!
List price: $14.00 (that's 20% off!)
Saving Emily is a wonderful novel for children aged 9 and up. In telling the stories of Emily, the heifer, 12-year-old Chris, and his friend Gina,Nicholas Read not only provides an interesting and enjoyable story, he also effectively informs the reader of the cruel existence that cows and bulls must endure until they are killed.
While Saving Emily is an interesting story and provides valuable insight into the business of growing and killing animals for food, it also deals with the important and common issues of dealing with—and overcoming, difficult childhood experiences. Chris must leave his friends and school in the city. His parents are divorced and his mother has married someone who lives in a small town. Gina is different from the other children in her school. She is a vegetarian and she helps out at the Rescue Ranch where dogs, horses and cows who have been saved are cared for. Her love for—and attitude toward, animals doesn’t sit well with the other students in the ranching community.
Finally, Saving Emily conveys the vital message that the efforts of a few can result in positive changes, making an often hostile and cruel world a little kinder. Children who like animals will enjoy this book. Children who aren’t as caring toward animals should read it! –Reviewed by Glenn Perrett
I'd recommend this as a must-read for all children, since they seem to be born with an inherent love for all animals.