The fact that this book was designed for researchers, who are involved in experimental (clinical) trials, makes the basic knowledge of statistics essential.
Using an interactive multidisciplinary approach to investigation, this handbook embraced all aspects clinical and paraclinical survey. It is very easy-to-follow, and divulges its methodology in concise manner. "Fundamentals of Clinical Trials" is one book that will help alleviate the rigorous chores of epidemiologists. However, an advanced or versatile researcher may complain that some of the information in it are too summarized.

I used this book for a class that I took last semester on clinical trial.

The authors do a good job of giving a good overview of the topics of interest, in particular: sample size calculation, use of DSMBs, trial design, choice of endpoints, randomization and issues in data analysis.

The chapters on sample size estimation and use of safety monitoring boards are quite heavy on the statistics. If you've never had an intro class in statistics, then these chapters may be way over your head.

There are a few topics that the authors didn't cover so well that I thought should have been more prominent: Choice of primary endpoints in FDA trials, general requirements of the FDA and regulatory information in general, the calculations of meta-analyses.

Overall I am quite happy with this book and will keep it on my shelf as a good reference.

This book is a very good place to start for those who want to learn about the design and analysis of clinical trials. However there is a heavy emphasis on statistics - a basic knowledge of stats is essential.

This book makes a great addition to anyone's GT40 collection. Friedman's pictures document not just the races, but a fair amount of the preparation necessary to get the cars in shape for competition.

As a pervious review mentioned, the coverage stops right after Ford's 1967 Le Mans win, thereby totally ignoring the JWA/Gulf era, but in all fairness, Shelby wasn't involved in those years. This is a book about the *Shelby* GT40 afterall.

I especially enjoyed some of the coverage of the GT40's competitors: Ferrari, Chapperal, and Porsche. This made the book just a little richer.

I became a fan of the Ford GT's on a sunday morning in June of 1966. I was 13 years old. Up early before my parents I turn on the T.V. to try to find some cartoons and lo and behold there in living color is the 24 hours of Le Mans. I did'nt really know much about it though the name Le Mans did mean something to me. I was enthralled. As the Ford Mk.II's finished 1,2,3, I became a Ford fan forever. This book recaptures those days and Ford's epic assault on Le Mans in pictures and captions. From the beginning of the program to the all-american victory in 1967 by Dan Gurney and A. J. Foyt in the Mk.IV. My only complaint is that the book ends abruptly with that victory. Boom. But like the jacket says, "to take a look inside is to take a trip back in time." And what a time it was.

Photographer David Friedman was around during the most important decade of the Indianapolis 500. With access to the track, stadium and pits that are long gone, Friedman shares his view of the rear engine revolution; the brilliant invasion of World Formula One Champions Brabham, Hill, Clark, Stewart and Rindt; and the triumphant partnership of Lotus and Ford.

The book has very little text, but the pictures bring life to a spectacular era in American racing.

Continuing with the exploration of culture, this is another jewel in the Feral House crown. There are only a few interviews, and they are rather outdated. Nonetheless, if you're a collector, this should be an invaluable reference. Lots and lots of reproductions of covers and some interior illustrations. Also, there is a small guide/checklist at the end to get you started.

This book should be required reading for aspiring dancers, particularly those who lack the administrative know-how to manage money, funding, etcetera. It teaches you everything they neglected to tell you in dance class. Makes a great gift!

"They Loved the Torah" is a MUST for biblical study! This beautifully written work asks the pivital question "Does God still expect us to live a Torah led life AFTER Yeshua came?"
He does an amazing job showing us the answer through the New Testement!

Dr. Friedman's thoughts will leave quite an impression on your mind and heart! Thank you for writing this book and I look forward to much more..........

I am a BIG fan of Deep Space Nine, so I obviously love to read Deep Space Nine books. But this one, well, wasn't so good. The plot is OK, and the characters are OK, but it just didn't do it for me. The Ro/Kira thing was good, but I didn't think it was right that Ro and Kira took on a whole criminal ring and won. Plus, I didn't think that Sisko would ever let Quark pilot the Defiant, so that was pretty dumb, and why would Sisko leave Deep Space Nine without a crew???? It just doesn't make sense. I'm not a fan of Friedman, and I don't know who the other two people are, but I just hope that the two of you break off relations with Friedman, and write a new Deep Space Nine book.

Originally Michelle Forbes was to go from Star Trek Next Generation to the Deep Space Nine show when she quit, Kira Nerys was created. So this book is sort of tongue in cheek. Unfortunately the blending of so many writers convolutes not the plot but the tone of the novel. Though it's not apparent who wrote what to avoid particular criticisms all of these writers, while versed in Star Trek have different styles.
So this book fails.

This book, which is a plot based around the first meeting of Kira and Ro Laren, is really good. I enjoyed their interactions a lot - they tease each other, act deliberately irritating, and say sarcastic things to each other, just like I'd imagine they would. But, eventually they realize they are more alike than different, which is as it should be. The plot was interesting - a plague caused by replicators, which is actually kind of a twist on the first season episode "Babel". I enjoyed the nice balance of action and character development. There weren't many problems, just two glaring ones - why were Kira and Ro hiking around Bajor on foot? Don't they have hovercars or something? The only explanation I can think of is that they wanted to be really, REALLY incognito. The other was that Sisko took only Quark as his crew on the Defiant. Surely the warship needs more than one person and one Ferengi to run it! And taking that fancy ship with its cloaking device into Orion space? That's just inviting them to steal it. They really should've taken a runabout! However, the writing quality was good, and it was a fun adventure to read. I recommend this novel to any DS9 or Ro Laren fan.

Doomsday World is by no means a bad Trek novel. Ordinarily, it would be entitled to the standard three stars that decent Trek novels are awarded. Unfortunately, the promise of having some of Trek's greatest novelists (Carter, David, and Friedman) teaming together falls way short of the mark. With few exceptions, each of their individual Trek novels have been several cuts above the norm; that Doomsday World never rises above the average makes the result all the more disappointing.

There are some good moments, including Worf saving the day with a barrage of phaser fire (then griping that if he'd been allowed to blast away when he'd wanted to they could have avoided a host of problems) and an amusing, if out of place, Monty Python reference ("What's the average air speed of an unladen swallow?" Geordi asks a bartender).

If you are going to read this one, do it because it's a Trek novel, not because of who the authors are . . . .

This book was written by Carmen Carter, Peter David, Michael Jan Friedman, and Robert Greenberger in concert. I expected a book written by committee to be sincerely bad. The four authors in question are all good enough to rescue this book from that fate, but almost any book by any one of them is better than this one.

Frankly, I thought that the concept was weak; I've read and enjoyed other "shared world" books, notably the "Thieves' World" series and the "Wild Cards" series, but in this case, ALL writing in the Star Trek universe already has all the advantages of such a concept, and I think that, left to themselves, we'd probably have gotten a novel at least as good as this one from EACH of these writers in the time it took us to get this one from the four of them.

The one possible reason for writing a novel this way is that it is potentially more fun for the authors than writing solo. I can see no other reason for the concept. Hopefully, having gotten this out of their systems, they'll go back to doing what they do best: writing solo.

Other reviews have focused on the fact that it took four writer to write this book. So what? It's no giant novel, but it's still a goo story with interesting bit players. The planet's many secrets have fun conclusions, and the characters are well written. I would expect this one would have made a better episode than novel, so try to imagine the visuals. I, for one, would like to see the dueling ambassadors again.

The 1999 reprint is a "Facsimile reprint"; the pictures appear to be photocopies of the original photographs - the quality is not up to Dave Friedman's norm. Some of the photos can be found in other publications; so, do not purchase this book for the photographs.

John Christy's narrative is informative and included a lot of stories/facts that I had not heard previously. It's style is very readable. If it were not for the pictures in the 1999 reprint, I would rate this book at 4 or 5 stars...