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It is very complete, there is no doubt about it. Every subject of medicine is covered, and for a reference book is a must-have. It is also written in an easy-to-read way, but some chapters are more difficult to understand than others, and like a good meal, in excess it can get heavy and occasionally become a brick, so slow-reading is advised. Also worth to mention are the atlases, that give a lot of pictographic information.
I would recommend it only as a reference book, because for the USMLE, or as a course textbook, it is impossible to read it all, especially if time is scarce.
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One of the things I found most helpful was the fact that each chapter begins with a list of key points to be presented in the chapter. These were a great help in keeping focused during the reading. I think anyone who bothered to do them would also find the questions at the end of each chapter to be very helpful. I tried to answer them regurlarly when preparing for tests found that they thoroughly covered the important material. Those along with the publisher's website were my key to success in the class I took. The final chapters do a good job of explaining statistics needed to write a research report (although I think a class in statistics is needed to really understand everything). There is also a complete, annotated research report at the end of the book which I also found very helpful (more helpful than the sample report provided in the APA style manual).
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